CJC-1295
CJC-1295 is a synthetic 29-residue analog of growth-hormone-releasing hormone, also known as Modified GRF (1-29), with a molecular weight of 3367.95 g/mol.
Identity & structure
Verified identifiers, sequence, and analytical properties — every value machine-readable and independently sourceable against PubChem.
Primary sequence · 29 residues · C-terminal amide · Mod-GRF(1-29): D-Ala2 · Gln8 · Ala15 · Nle27 — the substitutions that distinguish it from native GHRH(1-29).
| Identity | |
|---|---|
| CAS | 446036-97-1 |
| PubChem CID | 56841945 |
| FDA UNII | 62RC32V9N7 |
| Also known as | CJC1295, CJC 1295, CJC 1295 peptide, CJC-1295 without DAC, Modified GRF 1-29, Mod GRF 1-29, GRF 1-29 |
| Research class | Secretagogue & Regulatory |
| Structure | |
| Molecular formula | C152H252N44O42 |
| InChIKey | XOZMWINMZMMOBR-HRDSVTNWSA-N |
| Sequence | YADAIFTQSYRKVLAQLSARKLLQDILSR |
| Length | 29 residues |
| Analytical | |
| Average molecular weight | 3367.95 g/mol |
| Monoisotopic mass | 3365.8936 Da |
| Form | Lyophilized powder |
| Solubility | Water-soluble |
| Storage | 2–8 °C, desiccated |
Where CJC-1295 sits in its class
Molecular weight (g/mol) across the 21 characterized compounds in Secretagogue & Regulatory. Compare all compounds →
Research context
CJC-1295 is a synthetic 29-residue analog of growth-hormone-releasing hormone, also known as Modified GRF (1-29), with a molecular weight of 3367.95 g/mol. It differs from native GHRH(1-29) at four positions: D-alanine at 2, glutamine at 8, alanine at 15, and norleucine at 27. The C-terminus is amidated. Supplied as a characterized research material.
Not to be confused with: CJC-1295 DAC — Albumin-binding long-acting variant of Modified GRF (1-29). The compound Lineará stocks is the no-DAC form (CJC-1295 / Mod GRF 1-29); this DAC variant is listed here for characterization and disambiguation only.
Supplied solely as a characterized research material. No representation is made as to any biological effect. For Research Use Only — not for human or veterinary use.
How CJC-1295 is identified
Identity and purity are measured, not asserted. Electrospray mass spectrometry (ESI-MS) determines the mass-to-charge ratio of the intact molecule — an observed value matching the expected series above confirms the molecular formula. Reversed-phase HPLC separates the sample over time, and purity is read as arithmetic: the target peak’s area as a share of total peak area.
Handling & stability
Physical form, storage, and solubility as supplied. Handling guidance only — no use protocols.
Related compounds
Other compounds in this research class.
Frequently asked questions
What is CJC-1295?
What is the molecular formula of CJC-1295?
What is the CAS number of CJC-1295?
How is the identity of CJC-1295 confirmed?
How should CJC-1295 be stored?
Is CJC-1295 a peptide?
Is CJC-1295 approved for human use?
Data, tools & certificates
Research literature
Research literature — for reference only
Curated peer-reviewed references indexing the identity, characterization, and analytical-method literature for CJC-1295, from the U.S. National Library of Medicine (PubMed). Listed as neutral citations only — no findings, conclusions, or use are stated or implied.
- A method for confirming CJC-1295 abuse in equine plasma samples by LC-MS/MS.
- An immuno polymerase chain reaction screen for the detection of CJC-1295 and other growth-hormone-releasing hormone analogs in equine plasma.
- Identification of CJC-1295, a growth-hormone-releasing peptide, in an unknown pharmaceutical preparation.
- Analysis of growth hormone releasing hormone and its analogs in urine using nano liquid chromatography coupled with quadrupole/orbitrap mass spectrometry.
- Chromatographic-mass spectrometric analysis of peptidic analytes (2-10 kDa) in doping control urine samples.
- Cationic exchange SPE combined with triple quadrupole UHPLC-MS/MS for detection of GHRHs in urine samples.
- Probing for peptidic drugs (2-10 kDa) in doping control blood samples.
- An antibody-free, ultrafiltration-based assay for the detection of growth hormone-releasing hormones in urine at low pg/mL concentrations using nanoLC-HRMS/MS.
References
- PubChem — compound identity, structure & computed properties (CID 56841945). PubChem →
- CAS Registry Number 446036-97-1.
- FDA Global Substance Registration System — UNII 62RC32V9N7.
Research professionals only
CJC-1295 — from the record to the bench
The monograph and every lot certificate stay public. Pricing and ordering open for verified research professionals.