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Secretagogue & RegulatoryOpen access · public

AOD-9604

AOD-9604 is a synthetic 16-residue fragment of the C-terminus of human growth hormone, residues 176–191, with the molecular formula C78H123N23O23S2 and a molecular weight of 1815.10 g/mol.

CAS 221231-10-3Mol. weight 1815.10 g/molResearch Use Only
2D structure of AOD-9604 (PubChem CID 71300630)
2D structure via PubChem (CID 71300630). Public domain.
Computed 3D conformation (illustrative) · from the verified structure.

Identity & structure

Verified identifiers, sequence, and analytical properties — every value machine-readable and independently sourceable against PubChem.

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Primary sequence · 16 residues · disulfide bridge Cys7–Cys14.

AOD-9604 — identity and specification
Identity
CAS221231-10-3
PubChem CID71300630
FDA UNII7UP768IP4M
Also known asAOD9604, AOD 9604, AOD-9604 peptide, hGH Fragment 176-191, hGH Frag 176-191, Frag 176-191
Research classSecretagogue & Regulatory
Structure
Molecular formulaC78H123N23O23S2
InChIKeyGVIYUKXRXPXMQM-BPXGDYAESA-N
SequencehGH 176–191 fragment
Length16 residues
Analytical
Average molecular weight1815.10 g/mol
Monoisotopic mass1813.8604 Da
FormLyophilized powder
SolubilityWater-soluble
Storage2–8 °C, desiccated

Research context

AOD-9604 is a synthetic 16-residue fragment of the C-terminus of human growth hormone, residues 176–191, with the molecular formula C78H123N23O23S2 and a molecular weight of 1815.10 g/mol. It is studied in metabolic research and is supplied as a characterized reference material.

Supplied solely as a characterized research material. No representation is made as to any biological effect. For Research Use Only — not for human or veterinary use.

How AOD-9604 is identified

Identity and purity are measured, not asserted. Electrospray mass spectrometry (ESI-MS) determines the mass-to-charge ratio of the intact molecule — an observed value matching the expected series above confirms the molecular formula. Reversed-phase HPLC separates the sample over time, and purity is read as arithmetic: the target peak’s area as a share of total peak area.

IdentityESI-MS · observed vs expected m/z
PurityRP-HPLC · peak area %
CompositionMolecular formula · residue count

Handling & stability

Physical form, storage, and solubility as supplied. Handling guidance only — no use protocols.

Physical formLyophilized powder
Storage2–8 °C, desiccated
SolubilityWater-soluble
Length16 residues

Related compounds

Other compounds in this research class.

Frequently asked questions

What is AOD-9604?
AOD-9604 is a synthetic 16-residue fragment of the C-terminus of human growth hormone, residues 176–191, with the molecular formula C78H123N23O23S2 and a molecular weight of 1815.10 g/mol. It is studied in metabolic research and is supplied as a characterized reference material.
What is the molecular formula of AOD-9604?
AOD-9604 has the molecular formula C78H123N23O23S2, giving a molecular weight of 1815.10 g/mol. Its monoisotopic mass is 1813.8604 Da.
What is the CAS number of AOD-9604?
The CAS Registry Number for AOD-9604 is 221231-10-3. Its InChIKey is GVIYUKXRXPXMQM-BPXGDYAESA-N.
How is the identity of AOD-9604 confirmed?
Identity is confirmed by electrospray mass spectrometry. The observed mass-to-charge ratio is compared against the expected series — for AOD-9604, [M+H]⁺ is expected at m/z 1814.87. Purity is measured separately by reversed-phase HPLC as the target peak’s share of total peak area.
How should AOD-9604 be stored?
AOD-9604 is supplied as lyophilized powder and should be stored at 2–8 °C, desiccated. It is water-soluble.
Is AOD-9604 a peptide?
Yes. AOD-9604 is a peptide — a chain of amino-acid residues joined by peptide bonds, 16 residues in length. Its identity is defined by that sequence and its molecular mass.
Is AOD-9604 approved for human use?
No. AOD-9604 is supplied strictly for laboratory research use only. It is not a drug, is not approved by the FDA for any human or veterinary use, and must not be administered to humans or animals.

Data, tools & certificates

Research literature

Research literature — for reference only

Curated peer-reviewed references indexing the identity, characterization, and analytical-method literature for AOD-9604, from the U.S. National Library of Medicine (PubMed). Listed as neutral citations only — no findings, conclusions, or use are stated or implied.

  1. AOD-9604 does not influence the WADA hGH isoform immunoassay.
    Orlovius AK, Thomas A, Schänzer W, Thevis MDrug testing and analysis2013
  2. Simplifying and expanding the screening for peptides <2 kDa by direct urine injection, liquid chromatography, and ion mobility mass spectrometry.
    Thomas A, Görgens C, Guddat S, Thieme D, Dellanna F, Schänzer W, et al.Journal of separation science2016
  3. Detecting peptidic drugs, drug candidates and analogs in sports doping: current status and future directions.
    Thevis M, Thomas A, Schänzer WExpert review of proteomics2014

References

  1. PubChem — compound identity, structure & computed properties (CID 71300630). PubChem →
  2. CAS Registry Number 221231-10-3.
  3. FDA Global Substance Registration System — UNII 7UP768IP4M.

Research professionals only

AOD-9604 — from the record to the bench

The monograph and every lot certificate stay public. Pricing and ordering open for verified research professionals.

áFor Research Use Only · Not for human or veterinary use · Not for diagnostic or therapeutic use