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Secretagogue & RegulatoryOpen access · public

Tesamorelin

Tesamorelin is a 44-residue synthetic analog of growth-hormone-releasing hormone, with the molecular formula C221H366N72O67S and a molecular weight of 5135.86 g/mol.

CAS 218949-48-5Mol. weight 5135.86 g/molResearch Use Only
2D structure of Tesamorelin (PubChem CID 16137828)
2D structure via PubChem (CID 16137828). Public domain.
Computed 3D conformation (illustrative) · from the verified structure.

Identity & structure

Verified identifiers, sequence, and analytical properties — every value machine-readable and independently sourceable against PubChem.

hexenoyl–
Y
A
D
A
I
F
T
N
S
Y
R
K
V
L
G
Q
L
S
A
R
K
L
L
Q
D
I
M
S
R
Q
Q
G
E
S
N
Q
E
R
G
A
R
A
R
L
–NH₂

Primary sequence · 44 residues · N-terminal trans-3-hexenoyl · C-terminal amide.

Tesamorelin — identity and specification
Identity
CAS218949-48-5
PubChem CID16137828
FDA UNIIMQG94M5EEO
Also known asTesamorelin peptide, TH9507, TH-9507
Research classSecretagogue & Regulatory
Structure
Molecular formulaC221H366N72O67S
InChIKeyQBEPNUQJQWDYKU-BMGKTWPMSA-N
Sequence44-residue GHRH analog
Length44 residues
Analytical
Average molecular weight5135.86 g/mol
Monoisotopic mass5132.7166 Da
FormLyophilized powder
SolubilityWater-soluble
Storage2–8 °C, desiccated

Research context

Tesamorelin is a 44-residue synthetic analog of growth-hormone-releasing hormone, with the molecular formula C221H366N72O67S and a molecular weight of 5135.86 g/mol. It is supplied as a characterized research material and referenced in secretagogue research, with identity confirmed by mass spectrometry and purity measured by reversed-phase HPLC.

Supplied solely as a characterized research material. No representation is made as to any biological effect. For Research Use Only — not for human or veterinary use.

How Tesamorelin is identified

Identity and purity are measured, not asserted. Electrospray mass spectrometry (ESI-MS) determines the mass-to-charge ratio of the intact molecule — an observed value matching the expected series above confirms the molecular formula. Reversed-phase HPLC separates the sample over time, and purity is read as arithmetic: the target peak’s area as a share of total peak area.

IdentityESI-MS · observed vs expected m/z
PurityRP-HPLC · peak area %
CompositionMolecular formula · residue count

Handling & stability

Physical form, storage, and solubility as supplied. Handling guidance only — no use protocols.

Physical formLyophilized powder
Storage2–8 °C, desiccated
SolubilityWater-soluble
Length44 residues

Related compounds

Other compounds in this research class.

Frequently asked questions

What is Tesamorelin?
Tesamorelin is a 44-residue synthetic analog of growth-hormone-releasing hormone, with the molecular formula C221H366N72O67S and a molecular weight of 5135.86 g/mol. It is supplied as a characterized research material and referenced in secretagogue research, with identity confirmed by mass spectrometry and purity measured by reversed-phase HPLC.
What is the molecular formula of Tesamorelin?
Tesamorelin has the molecular formula C221H366N72O67S, giving a molecular weight of 5135.86 g/mol. Its monoisotopic mass is 5132.7166 Da.
What is the CAS number of Tesamorelin?
The CAS Registry Number for Tesamorelin is 218949-48-5. Its InChIKey is QBEPNUQJQWDYKU-BMGKTWPMSA-N.
How is the identity of Tesamorelin confirmed?
Identity is confirmed by electrospray mass spectrometry. The observed mass-to-charge ratio is compared against the expected series — for Tesamorelin, [M+H]⁺ is expected at m/z 5133.72. Purity is measured separately by reversed-phase HPLC as the target peak’s share of total peak area.
How should Tesamorelin be stored?
Tesamorelin is supplied as lyophilized powder and should be stored at 2–8 °C, desiccated. It is water-soluble.
Is Tesamorelin a peptide?
Yes. Tesamorelin is a peptide — a chain of amino-acid residues joined by peptide bonds, 44 residues in length. Its identity is defined by that sequence and its molecular mass.
Is Tesamorelin approved for human use?
No. Tesamorelin is supplied strictly for laboratory research use only. It is not a drug, is not approved by the FDA for any human or veterinary use, and must not be administered to humans or animals.

Data, tools & certificates

Research literature

Research literature — for reference only

Curated peer-reviewed references indexing the identity, characterization, and analytical-method literature for Tesamorelin, from the U.S. National Library of Medicine (PubMed). Listed as neutral citations only — no findings, conclusions, or use are stated or implied.

  1. Advances in the detection of growth hormone releasing hormone synthetic analogs.
    Memdouh S, Gavrilović I, Ng K, Cowan D, Abbate VDrug testing and analysis2021

References

  1. PubChem — compound identity, structure & computed properties (CID 16137828). PubChem →
  2. CAS Registry Number 218949-48-5.
  3. FDA Global Substance Registration System — UNII MQG94M5EEO.

Research professionals only

Tesamorelin — from the record to the bench

The monograph and every lot certificate stay public. Pricing and ordering open for verified research professionals.

áFor Research Use Only · Not for human or veterinary use · Not for diagnostic or therapeutic use