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Pancragen

Pancragen is a synthetic tetrapeptide, H-Lys-Glu-Asp-Trp-OH (single-letter KEDW), of L-lysine, L-glutamic acid, L-aspartic acid and L-tryptophan, supplied as the free acid, from the St.

CAS Mol. weight 576.61 g/molResearch Use Only · reference
2D structure of Pancragen (computed from the verified SMILES)
2D depiction computed with RDKit from the verified SMILES.

Identity & structure

K
E
D
W

Primary sequence · 4 residues.

Pancragen — identity and specification
Identity
CAS
Also known asPancragen peptide, Lys-Glu-Asp-Trp, KEDW, KEDW peptide
Research classSecretagogue & Regulatory
Structure
Molecular formulaC26H36N6O9
SequenceLys-Glu-Asp-Trp
Length4 residues
Analytical
Average molecular weight576.61 g/mol
Monoisotopic mass576.2544 Da (computed)

The free tetrapeptide H-Lys-Glu-Asp-Trp-OH (single-letter KEDW), of L-lysine, L-glutamic acid, L-aspartic acid and L-tryptophan with free termini, molecular formula C26H36N6O9. The chemist confirms the supplied form is the free acid. Chemical registries index the C-terminal AMIDE instead: PubChem CID 68451868 is H-Lys-Glu-Asp-Trp-NH2, a different molecule (C26H37N7O8, InChIKey WKJHPWJUFPYRSF-LEAZDLGRSA-N), so that CID is not shipped as this entity's identifier and no CID is asserted for the free acid here (a free-acid record surfaced by live PUG-REST at build is noted in the identifiers report). The sequence-derived structure carries no unassigned stereocentres. A computed 3D conformer is held pending the chemist sign-off.

Reference context

Pancragen is a synthetic tetrapeptide, H-Lys-Glu-Asp-Trp-OH (single-letter KEDW), of L-lysine, L-glutamic acid, L-aspartic acid and L-tryptophan, supplied as the free acid, from the St. Petersburg (Khavinson) line of short peptide bioregulators. It is listed here strictly as an analytical reference entity — it is not sold, stocked, or certified by Lineará, and has no price or certificate of analysis. The data on this page is characterization only: molecular formula C26H36N6O9 and the values computed from it. No biological activity, mechanism, or use is described or implied.

Listed solely as a characterized analytical reference — no representation is made as to any biological effect. For Research Use Only — not for human or veterinary use.

How Pancragen is characterized

Identity rests on the molecular formula and mass. Electrospray mass spectrometry (ESI-MS) measures the mass-to-charge ratio of the intact molecule; the average and monoisotopic masses are computed from the verified formula and cross-check the composition. The residue sequence and the modifications noted above define the structure.

CompositionMolecular formula · 4-residue peptide
MassAverage & monoisotopic · ESI-MS
IdentityCAS

Frequently asked questions

What is Pancragen?
Pancragen is a synthetic tetrapeptide, H-Lys-Glu-Asp-Trp-OH (single-letter KEDW), of L-lysine, L-glutamic acid, L-aspartic acid and L-tryptophan, supplied as the free acid, from the St. Petersburg (Khavinson) line of short peptide bioregulators. It is listed here strictly as an analytical reference entity — it is not sold, stocked, or certified by Lineará, and has no price or certificate of analysis. The data on this page is characterization only: molecular formula C26H36N6O9 and the values computed from it. No biological activity, mechanism, or use is described or implied.
What is the amino-acid sequence of Pancragen?
Pancragen has the sequence Lys-Glu-Asp-Trp. The free tetrapeptide H-Lys-Glu-Asp-Trp-OH (single-letter KEDW), of L-lysine, L-glutamic acid, L-aspartic acid and L-tryptophan with free termini, molecular formula C26H36N6O9. The chemist confirms the supplied form is the free acid. Chemical registries index the C-terminal AMIDE instead: PubChem CID 68451868 is H-Lys-Glu-Asp-Trp-NH2, a different molecule (C26H37N7O8, InChIKey WKJHPWJUFPYRSF-LEAZDLGRSA-N), so that CID is not shipped as this entity's identifier and no CID is asserted for the free acid here (a free-acid record surfaced by live PUG-REST at build is noted in the identifiers report). The sequence-derived structure carries no unassigned stereocentres. A computed 3D conformer is held pending the chemist sign-off.
What is the molecular formula of Pancragen?
Pancragen has the molecular formula C26H36N6O9, giving an average molecular weight of 576.61 g/mol and a computed monoisotopic mass of 576.2544 Da.
Is Pancragen a peptide?
Yes. Pancragen is a peptide — a chain of amino-acid residues joined by peptide bonds, 4 residues in length. Its identity is defined by that sequence and its molecular mass.
How is Pancragen stored and reconstituted?
As a research material, Pancragen is typically handled as a lyophilized (freeze-dried) powder. It is kept desiccated and cold — commonly 2–8 °C for short periods and −20 °C for longer storage — and reconstituted in sterile or bacteriostatic water. This is storage and handling information only, not a use protocol.
Does Lineará sell Pancragen?
No. Pancragen is listed here only as an analytical reference entity. It is not part of the Lineará formulary, has no price or certificate of analysis, and is not offered for sale.
Is Pancragen approved for human use?
No. Pancragen is presented strictly as characterization reference data. It is not a drug, is not approved for any human or veterinary use, and must not be administered to humans or animals.

Data, tools & related references

References

    Research professionals only

    Reference data

    This monograph is characterization reference data. Lineará does not sell, stock, or certify Pancragen.

    áFor Research Use Only · Not for human or veterinary use · Not for diagnostic or therapeutic use