Kisspeptin-10
Kisspeptin-10 is the ten-residue C-terminal fragment of the KISS1 gene product, the C-terminally amidated decapeptide Tyr-Asn-Trp-Asn-Ser-Phe-Gly-Leu-Arg-Phe-NH2 (YNWNSFGLRF-NH2), ending in the Arg-Phe-amide motif that defines the kisspeptin family.
Identity & structure
Primary sequence · 10 residues · C-terminal amide · Decapeptide amide (YNWNSFGLRF-NH2); the C-terminal Arg-Phe-amide is the RF-amide motif shared across the kisspeptin family. Corresponds to residues 45-54 of kisspeptin-54 (metastin)..
| Identity | |
|---|---|
| CAS | 374675-21-5 |
| PubChem CID | 25240297 |
| Also known as | Metastin (45-54), Metastin (45-54) amide, Kisspeptin-10 (human), KiSS-1 (112-121), Kisspeptin-10 peptide, Kisspeptin 10 |
| Research class | Secretagogue & Regulatory |
| Structure | |
| Molecular formula | C63H83N17O14 |
| InChIKey | RITKWYDZSSQNJI-INXYWQKQSA-N |
| Sequence | Tyr-Asn-Trp-Asn-Ser-Phe-Gly-Leu-Arg-Phe-NH2 |
| Length | 10 residues |
| Analytical | |
| Average molecular weight | 1302.44 g/mol |
| Monoisotopic mass | 1301.6305 Da (computed) |
A C-terminally amidated decapeptide, written in single-letter form as YNWNSFGLRF-NH2. It is the C-terminal ten residues of kisspeptin-54 — the full-length KISS1 gene product also called metastin — and retains the amidated Arg-Phe (RF-amide) motif shared across the kisspeptin family; the synonym "Metastin (45-54)" names exactly those ten residues. Its nine stereocentres are all L-configured (glycine at position 7 is achiral). The human decapeptide is the record used here; the rat analog is a distinct compound with a different formula.
Reference context
Kisspeptin-10 is the ten-residue C-terminal fragment of the KISS1 gene product, the C-terminally amidated decapeptide Tyr-Asn-Trp-Asn-Ser-Phe-Gly-Leu-Arg-Phe-NH2 (YNWNSFGLRF-NH2), ending in the Arg-Phe-amide motif that defines the kisspeptin family. It is listed here strictly as an analytical reference entity — it is not sold, stocked, or certified by Lineará, and has no price or certificate of analysis. The data on this page is characterization only: molecular formula C63H83N17O14 and the values computed from it. No biological activity, mechanism, or use is described or implied.
Listed solely as a characterized analytical reference — no representation is made as to any biological effect. For Research Use Only — not for human or veterinary use.
How Kisspeptin-10 is characterized
Identity rests on the molecular formula and mass. Electrospray mass spectrometry (ESI-MS) measures the mass-to-charge ratio of the intact molecule; the average and monoisotopic masses are computed from the verified formula and cross-check the composition. The residue sequence and the modifications noted above define the structure.
Frequently asked questions
What is Kisspeptin-10?
What is the amino-acid sequence of Kisspeptin-10?
What is the molecular formula of Kisspeptin-10?
What are the key chemical identifiers for Kisspeptin-10?
Is Kisspeptin-10 a peptide?
How is Kisspeptin-10 stored and reconstituted?
Does Lineará sell Kisspeptin-10?
Is Kisspeptin-10 approved for human use?
Data, tools & related references
References
- PubChem — compound identity, structure & computed properties (CID 25240297). PubChem →
- CAS Registry Number 374675-21-5.
Research professionals only
Reference data
This monograph is characterization reference data. Lineará does not sell, stock, or certify Kisspeptin-10.