Adipotide
Adipotide is a synthetic chimeric peptidomimetic that joins a disulfide-cyclized prohibitin-homing nonapeptide, CKGGRAKDC, through a Gly-Gly linker to a pro-apoptotic domain of D-amino acids written D(KLAKLAK)2, for 25 residues in total.

Identity & structure
Primary sequence · 25 residues · disulfide bridge Cys1–Cys9 · 25-residue chimeric peptide: a disulfide-cyclized prohibitin-homing loop CKGGRAKDC (Cys1-Cys9 bridge), a Gly-Gly linker, and a pro-apoptotic domain (KLAKLAK)2 built entirely of D-amino acids. The leading "D" in D(KLAKLAK)2 is a D-enantiomer prefix, not an aspartate. Free-acid C-terminus; the disulfide-cyclized form is canonical (PubChem CID 163360068 is the reduced open-thiol form)..
| Identity | |
|---|---|
| CAS | 859216-15-2 |
| PubChem CID | 163360068 |
| Also known as | FTPP, Prohibitin-targeting peptide 1, Prohibitin-TP01, Adipotide peptide |
| Research class | Secretagogue & Regulatory |
| Structure | |
| Molecular formula | C111H204N36O28S2 |
| Sequence | CKGGRAKDC-GG-D(KLAKLAK)2 |
| Length | 25 residues |
| Analytical | |
| Average molecular weight | 2555.21 g/mol |
| Monoisotopic mass | 2553.5087 Da (computed) |
Adipotide is a two-part molecule: a nonapeptide homing loop, CKGGRAKDC, closed by a disulfide bond between its two cysteines, joined through a Gly-Gly linker to a pro-apoptotic domain written D(KLAKLAK)2 — two tandem KLAKLAK repeats built entirely from D-amino acids. The leading "D" on that domain is a D-enantiomer prefix, not an aspartate residue. The canonical form shown here is the disulfide-cyclized peptide, molecular formula C111H204N36O28S2 (average mass 2555.21 g/mol, free-acid C-terminus). PubChem CID 163360068 deposits the reduced, open-thiol form of the same 25-residue sequence, C111H206N36O28S2 — two hydrogens heavier — which computes exactly from the sequence and confirms the composition; the cyclized form removes those two hydrogens on forming the S–S bond. No machine-verified InChIKey is published: for a large multi-part peptide whose canonical oxidation state differs from the deposited record, a single small-molecule key would misstate the entity, so it is represented by its verified sequence and formula instead.
Reference context
Adipotide is a synthetic chimeric peptidomimetic that joins a disulfide-cyclized prohibitin-homing nonapeptide, CKGGRAKDC, through a Gly-Gly linker to a pro-apoptotic domain of D-amino acids written D(KLAKLAK)2, for 25 residues in total. It is listed here strictly as an analytical reference entity — it is not sold, stocked, or certified by Lineará, and has no price or certificate of analysis. The data on this page is characterization only: molecular formula C111H204N36O28S2 and the values computed from it. No biological activity, mechanism, or use is described or implied.
Listed solely as a characterized analytical reference — no representation is made as to any biological effect. For Research Use Only — not for human or veterinary use.
How Adipotide is characterized
Identity rests on the molecular formula and mass. Electrospray mass spectrometry (ESI-MS) measures the mass-to-charge ratio of the intact molecule; the average and monoisotopic masses are computed from the verified formula and cross-check the composition. The residue sequence and the modifications noted above define the structure.
Frequently asked questions
What is Adipotide?
What is the amino-acid sequence of Adipotide?
What is the molecular formula of Adipotide?
What are the key chemical identifiers for Adipotide?
Is Adipotide a peptide?
How is Adipotide stored and reconstituted?
Does Lineará sell Adipotide?
Is Adipotide approved for human use?
Data, tools & related references
References
- PubChem — compound identity, structure & computed properties (CID 163360068). PubChem →
- CAS Registry Number 859216-15-2.
Research professionals only
Reference data
This monograph is characterization reference data. Lineará does not sell, stock, or certify Adipotide.