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Secretagogue & RegulatoryOpen access · public

MOTS-c

MOTS-c is a mitochondrial-derived peptide of sixteen residues, with the molecular formula C101H152N28O22S2 and a molecular weight of 2174.62 g/mol.

CAS 1627580-64-6Mol. weight 2174.62 g/molResearch Use Only
2D structure of MOTS-c (PubChem CID 146675088)
2D structure via PubChem (CID 146675088). Public domain.
Computed 3D conformation (illustrative) · from the verified structure.

Identity & structure

Verified identifiers, sequence, and analytical properties — every value machine-readable and independently sourceable against PubChem.

M
R
W
Q
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M
G
Y
I
F
Y
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Primary sequence · 16 residues.

MOTS-c — identity and specification
Identity
CAS1627580-64-6
PubChem CID146675088
FDA UNIIA5CV6JFB78
Also known asMOTS c, MOTSc, MOTS-c peptide, MOTS-c (human), Mitochondria-derived peptide MOTS-c
Research classSecretagogue & Regulatory
Structure
Molecular formulaC101H152N28O22S2
InChIKeyWYTHCOXVWRKRAH-LOKRTKBUSA-N
Sequence16-residue peptide
Length16 residues
Analytical
Average molecular weight2174.62 g/mol
Monoisotopic mass2173.1077 Da
FormLyophilized powder
SolubilityWater-soluble
Storage2–8 °C, desiccated

Research context

MOTS-c is a mitochondrial-derived peptide of sixteen residues, with the molecular formula C101H152N28O22S2 and a molecular weight of 2174.62 g/mol. It is studied in metabolic and mitochondrial research as a synthetic reference compound and is supplied as a lyophilized, characterized material.

Supplied solely as a characterized research material. No representation is made as to any biological effect. For Research Use Only — not for human or veterinary use.

How MOTS-c is identified

Identity and purity are measured, not asserted. Electrospray mass spectrometry (ESI-MS) determines the mass-to-charge ratio of the intact molecule — an observed value matching the expected series above confirms the molecular formula. Reversed-phase HPLC separates the sample over time, and purity is read as arithmetic: the target peak’s area as a share of total peak area.

IdentityESI-MS · observed vs expected m/z
PurityRP-HPLC · peak area %
CompositionMolecular formula · residue count

Handling & stability

Physical form, storage, and solubility as supplied. Handling guidance only — no use protocols.

Physical formLyophilized powder
Storage2–8 °C, desiccated
SolubilityWater-soluble
Length16 residues

Related compounds

Other compounds in this research class.

Frequently asked questions

What is MOTS-c?
MOTS-c is a mitochondrial-derived peptide of sixteen residues, with the molecular formula C101H152N28O22S2 and a molecular weight of 2174.62 g/mol. It is studied in metabolic and mitochondrial research as a synthetic reference compound and is supplied as a lyophilized, characterized material.
What is the molecular formula of MOTS-c?
MOTS-c has the molecular formula C101H152N28O22S2, giving a molecular weight of 2174.62 g/mol. Its monoisotopic mass is 2173.1077 Da.
What is the CAS number of MOTS-c?
The CAS Registry Number for MOTS-c is 1627580-64-6. Its InChIKey is WYTHCOXVWRKRAH-LOKRTKBUSA-N.
How is the identity of MOTS-c confirmed?
Identity is confirmed by electrospray mass spectrometry. The observed mass-to-charge ratio is compared against the expected series — for MOTS-c, [M+H]⁺ is expected at m/z 2174.12. Purity is measured separately by reversed-phase HPLC as the target peak’s share of total peak area.
How should MOTS-c be stored?
MOTS-c is supplied as lyophilized powder and should be stored at 2–8 °C, desiccated. It is water-soluble.
Is MOTS-c a peptide?
Yes. MOTS-c is a peptide — a chain of amino-acid residues joined by peptide bonds, 16 residues in length. Its identity is defined by that sequence and its molecular mass.
Is MOTS-c approved for human use?
No. MOTS-c is supplied strictly for laboratory research use only. It is not a drug, is not approved by the FDA for any human or veterinary use, and must not be administered to humans or animals.

Data, tools & certificates

References

  1. PubChem — compound identity, structure & computed properties (CID 146675088). PubChem →
  2. CAS Registry Number 1627580-64-6.
  3. FDA Global Substance Registration System — UNII A5CV6JFB78.

Research professionals only

MOTS-c — from the record to the bench

The monograph and every lot certificate stay public. Pricing and ordering open for verified research professionals.

áFor Research Use Only · Not for human or veterinary use · Not for diagnostic or therapeutic use