Gonadorelin
Gonadorelin is a synthetic decapeptide, pGlu-His-Trp-Ser-Tyr-Gly-Leu-Arg-Pro-Gly-NH2, corresponding to gonadotropin-releasing hormone (GnRH / LHRH) - a ten-residue peptide with an N-terminal pyroglutamate and a C-terminal glycinamide.

Identity & structure
Primary sequence · 10 residues · C-terminal amide · Decapeptide amide with an N-terminal pyroglutamate (pGlu, a cyclized glutamine) and a C-terminal glycinamide; the gonadotropin-releasing hormone (GnRH / LHRH) sequence..
| Identity | |
|---|---|
| CAS | 33515-09-2 |
| PubChem CID | 638793 |
| FDA UNII | 9O7312W37G |
| Also known as | GnRH, LHRH, LH-RH, Luteinizing hormone-releasing hormone, Gonadotropin-releasing hormone, Gonadoliberin, Gonadorelin acetate, Gonadorelin peptide |
| Research class | Secretagogue & Regulatory |
| Structure | |
| Molecular formula | C55H75N17O13 |
| InChIKey | XLXSAKCOAKORKW-AQJXLSMYSA-N |
| Sequence | pGlu-His-Trp-Ser-Tyr-Gly-Leu-Arg-Pro-Gly-NH2 |
| Length | 10 residues |
| Analytical | |
| Average molecular weight | 1182.31 g/mol |
| Monoisotopic mass | 1181.5730 Da (computed) |
A decapeptide amide, pGlu-His-Trp-Ser-Tyr-Gly-Leu-Arg-Pro-Gly-NH2, carrying two end-group modifications visible on any characterization: an N-terminal pyroglutamate (a cyclized glutamine residue) and a C-terminal glycinamide. This is the sequence named gonadotropin-releasing hormone (GnRH / LHRH), for which gonadorelin is the International Nonproprietary Name; molecular formula C55H75N17O13. Identity is reconciled against PubChem CID 638793 (CAS 33515-09-2, the free peptide; the acetate salt carries the secondary CAS 51952-41-1): the stereo-defined InChIKey XLXSAKCOAKORKW-AQJXLSMYSA-N matches the deposited record exactly. A computed 3D conformer is held pending the chemist sign-off, and any unassigned stereocentre is to be confirmed at that review.
Reference context
Gonadorelin is a synthetic decapeptide, pGlu-His-Trp-Ser-Tyr-Gly-Leu-Arg-Pro-Gly-NH2, corresponding to gonadotropin-releasing hormone (GnRH / LHRH) - a ten-residue peptide with an N-terminal pyroglutamate and a C-terminal glycinamide. It is listed here strictly as an analytical reference entity — it is not sold, stocked, or certified by Lineará, and has no price or certificate of analysis. The data on this page is characterization only: molecular formula C55H75N17O13 and the values computed from it. No biological activity, mechanism, or use is described or implied.
Listed solely as a characterized analytical reference — no representation is made as to any biological effect. For Research Use Only — not for human or veterinary use.
How Gonadorelin is characterized
Identity rests on the molecular formula and mass. Electrospray mass spectrometry (ESI-MS) measures the mass-to-charge ratio of the intact molecule; the average and monoisotopic masses are computed from the verified formula and cross-check the composition. The residue sequence and the modifications noted above define the structure.
Frequently asked questions
What is Gonadorelin?
What is the amino-acid sequence of Gonadorelin?
What is the molecular formula of Gonadorelin?
What are the key chemical identifiers for Gonadorelin?
Is Gonadorelin a peptide?
How is Gonadorelin stored and reconstituted?
Does Lineará sell Gonadorelin?
Is Gonadorelin approved for human use?
Data, tools & related references
References
- PubChem — compound identity, structure & computed properties (CID 638793). PubChem →
- CAS Registry Number 33515-09-2.
- FDA Global Substance Registration System — UNII 9O7312W37G.
Research professionals only
Reference data
This monograph is characterization reference data. Lineará does not sell, stock, or certify Gonadorelin.