Lineará
Secretagogue & RegulatoryOpen access · public

Gonadorelin

Gonadorelin is a synthetic decapeptide, pGlu-His-Trp-Ser-Tyr-Gly-Leu-Arg-Pro-Gly-NH2, corresponding to gonadotropin-releasing hormone (GnRH / LHRH) - a ten-residue peptide with an N-terminal pyroglutamate and a C-terminal glycinamide.

CAS 33515-09-2Mol. weight 1182.31 g/molResearch Use Only · reference
2D structure of Gonadorelin (PubChem CID 638793)
2D structure via PubChem (CID 638793). Public domain.

Identity & structure

pGlu
H
W
S
Y
G
L
R
P
G
–NH₂

Primary sequence · 10 residues · C-terminal amide · Decapeptide amide with an N-terminal pyroglutamate (pGlu, a cyclized glutamine) and a C-terminal glycinamide; the gonadotropin-releasing hormone (GnRH / LHRH) sequence..

Gonadorelin — identity and specification
Identity
CAS33515-09-2
PubChem CID638793
FDA UNII9O7312W37G
Also known asGnRH, LHRH, LH-RH, Luteinizing hormone-releasing hormone, Gonadotropin-releasing hormone, Gonadoliberin, Gonadorelin acetate, Gonadorelin peptide
Research classSecretagogue & Regulatory
Structure
Molecular formulaC55H75N17O13
InChIKeyXLXSAKCOAKORKW-AQJXLSMYSA-N
SequencepGlu-His-Trp-Ser-Tyr-Gly-Leu-Arg-Pro-Gly-NH2
Length10 residues
Analytical
Average molecular weight1182.31 g/mol
Monoisotopic mass1181.5730 Da (computed)

A decapeptide amide, pGlu-His-Trp-Ser-Tyr-Gly-Leu-Arg-Pro-Gly-NH2, carrying two end-group modifications visible on any characterization: an N-terminal pyroglutamate (a cyclized glutamine residue) and a C-terminal glycinamide. This is the sequence named gonadotropin-releasing hormone (GnRH / LHRH), for which gonadorelin is the International Nonproprietary Name; molecular formula C55H75N17O13. Identity is reconciled against PubChem CID 638793 (CAS 33515-09-2, the free peptide; the acetate salt carries the secondary CAS 51952-41-1): the stereo-defined InChIKey XLXSAKCOAKORKW-AQJXLSMYSA-N matches the deposited record exactly. A computed 3D conformer is held pending the chemist sign-off, and any unassigned stereocentre is to be confirmed at that review.

Reference context

Gonadorelin is a synthetic decapeptide, pGlu-His-Trp-Ser-Tyr-Gly-Leu-Arg-Pro-Gly-NH2, corresponding to gonadotropin-releasing hormone (GnRH / LHRH) - a ten-residue peptide with an N-terminal pyroglutamate and a C-terminal glycinamide. It is listed here strictly as an analytical reference entity — it is not sold, stocked, or certified by Lineará, and has no price or certificate of analysis. The data on this page is characterization only: molecular formula C55H75N17O13 and the values computed from it. No biological activity, mechanism, or use is described or implied.

Listed solely as a characterized analytical reference — no representation is made as to any biological effect. For Research Use Only — not for human or veterinary use.

How Gonadorelin is characterized

Identity rests on the molecular formula and mass. Electrospray mass spectrometry (ESI-MS) measures the mass-to-charge ratio of the intact molecule; the average and monoisotopic masses are computed from the verified formula and cross-check the composition. The residue sequence and the modifications noted above define the structure.

CompositionMolecular formula · 10-residue peptide
MassAverage & monoisotopic · ESI-MS
IdentityCAS · PubChem CID · UNII · InChIKey

Frequently asked questions

What is Gonadorelin?
Gonadorelin is a synthetic decapeptide, pGlu-His-Trp-Ser-Tyr-Gly-Leu-Arg-Pro-Gly-NH2, corresponding to gonadotropin-releasing hormone (GnRH / LHRH) - a ten-residue peptide with an N-terminal pyroglutamate and a C-terminal glycinamide. It is listed here strictly as an analytical reference entity — it is not sold, stocked, or certified by Lineará, and has no price or certificate of analysis. The data on this page is characterization only: molecular formula C55H75N17O13 and the values computed from it. No biological activity, mechanism, or use is described or implied.
What is the amino-acid sequence of Gonadorelin?
Gonadorelin has the sequence pGlu-His-Trp-Ser-Tyr-Gly-Leu-Arg-Pro-Gly-NH2. A decapeptide amide, pGlu-His-Trp-Ser-Tyr-Gly-Leu-Arg-Pro-Gly-NH2, carrying two end-group modifications visible on any characterization: an N-terminal pyroglutamate (a cyclized glutamine residue) and a C-terminal glycinamide. This is the sequence named gonadotropin-releasing hormone (GnRH / LHRH), for which gonadorelin is the International Nonproprietary Name; molecular formula C55H75N17O13. Identity is reconciled against PubChem CID 638793 (CAS 33515-09-2, the free peptide; the acetate salt carries the secondary CAS 51952-41-1): the stereo-defined InChIKey XLXSAKCOAKORKW-AQJXLSMYSA-N matches the deposited record exactly. A computed 3D conformer is held pending the chemist sign-off, and any unassigned stereocentre is to be confirmed at that review.
What is the molecular formula of Gonadorelin?
Gonadorelin has the molecular formula C55H75N17O13, giving an average molecular weight of 1182.31 g/mol and a computed monoisotopic mass of 1181.5730 Da.
What are the key chemical identifiers for Gonadorelin?
The CAS Registry Number for Gonadorelin is 33515-09-2. Its PubChem CID is 638793, its FDA UNII is 9O7312W37G, and its InChIKey is XLXSAKCOAKORKW-AQJXLSMYSA-N.
Is Gonadorelin a peptide?
Yes. Gonadorelin is a peptide — a chain of amino-acid residues joined by peptide bonds, 10 residues in length. Its identity is defined by that sequence and its molecular mass.
How is Gonadorelin stored and reconstituted?
As a research material, Gonadorelin is typically handled as a lyophilized (freeze-dried) powder. It is kept desiccated and cold — commonly 2–8 °C for short periods and −20 °C for longer storage — and reconstituted in sterile or bacteriostatic water. This is storage and handling information only, not a use protocol.
Does Lineará sell Gonadorelin?
No. Gonadorelin is listed here only as an analytical reference entity. It is not part of the Lineará formulary, has no price or certificate of analysis, and is not offered for sale.
Is Gonadorelin approved for human use?
No. Gonadorelin is presented strictly as characterization reference data. It is not a drug, is not approved for any human or veterinary use, and must not be administered to humans or animals.

Data, tools & related references

References

  1. PubChem — compound identity, structure & computed properties (CID 638793). PubChem →
  2. CAS Registry Number 33515-09-2.
  3. FDA Global Substance Registration System — UNII 9O7312W37G.

Research professionals only

Reference data

This monograph is characterization reference data. Lineará does not sell, stock, or certify Gonadorelin.

áFor Research Use Only · Not for human or veterinary use · Not for diagnostic or therapeutic use