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CJC-1295 DAC

CJC-1295 DAC is an albumin-binding, long-acting variant of Modified GRF (1-29): the same growth-hormone-releasing-hormone backbone as the no-DAC form, extended at Lys30 with an Nε-3-maleimidopropionyl Drug Affinity Complex (DAC) linker.

CAS 446262-90-4Mol. weight 3647.20 g/molResearch Use Only · reference
2D structure of CJC-1295 DAC (PubChem CID 91971820)
2D structure via PubChem (CID 91971820). Public domain.
Computed 3D conformation (illustrative) · from the verified structure.

Identity & structure

Y
D-Ala
D
A
I
F
T
Q
S
Y
R
K
V
L
A
Q
L
S
A
R
K
L
L
Q
D
I
Nle
S
R
K
–NH₂

Primary sequence · 30 residues · C-terminal amide · Mod-GRF(1-29) backbone (D-Ala2 · Gln8 · Ala15 · Nle27) extended by Lys30, whose ε-amine carries the 3-maleimidopropionyl DAC linker — the maleimide is not expressible as a residue and is not shown.

CJC-1295 DAC — identity and specification
Identity
CAS446262-90-4
PubChem CID91971820
FDA UNII62RC32V9N7
Also known asCJC-1295 with DAC, CJC 1295 DAC, CJC-1295 DAC, DAC:GRF, CJC-1295 DAC peptide
Research classSecretagogue & Regulatory
Structure
Molecular formulaC165H269N47O46
InChIKeyZUQGTWKGESAQCD-ZGFIGYLBSA-N
SequenceMod GRF (1-29) backbone + Lys30 (Nε-3-maleimidopropionyl DAC linker)
Length30 residues
Analytical
Average molecular weight3647.20 g/mol
Monoisotopic mass3645.0155 Da (computed)

The 29-residue Modified GRF (1-29) backbone (as in the no-DAC form) extended by a 30th residue, Lys30, whose ε-amine carries a 3-maleimidopropionyl "Drug Affinity Complex" (DAC) group — an albumin-binding linker. The maleimide is not expressible in a plain single-letter sequence string.

Disambiguation

CJC-1295 DAC is an albumin-binding, long-acting variant of Modified GRF (1-29): the same growth-hormone-releasing-hormone backbone as the no-DAC form, extended at Lys30 with an Nε-3-maleimidopropionyl Drug Affinity Complex (DAC) linker. It is listed here strictly as an analytical reference and disambiguation entry — it is not sold, stocked, or certified by Lineará, and has no price or certificate of analysis. The data on this page is characterization only: molecular formula C165H269N47O46 and the values computed from it. It is a distinct chemical form from CJC-1295 (no DAC), which Lineará stocks and characterizes separately.

Not to be confused with CJC-1295 (no DAC). Albumin-binding long-acting variant of Modified GRF (1-29). The compound Lineará stocks is the no-DAC form (CJC-1295 / Mod GRF 1-29); this DAC variant is listed here for characterization and disambiguation only. Listed solely as a characterized analytical reference — no representation is made as to any biological effect. For Research Use Only — not for human or veterinary use.

View CJC-1295 (no DAC) →

How CJC-1295 DAC is characterized

Identity rests on the molecular formula and mass. Electrospray mass spectrometry (ESI-MS) measures the mass-to-charge ratio of the intact molecule; the average and monoisotopic masses are computed from the verified formula and cross-check the composition. The residue sequence and the modifications noted above define the structure.

CompositionMolecular formula · 30-residue peptide
MassAverage & monoisotopic · ESI-MS
IdentityCAS · PubChem CID · UNII · InChIKey
Computed mass & m/z →How an HPLC trace is read →

Frequently asked questions

What is CJC-1295 DAC?
CJC-1295 DAC is an albumin-binding, long-acting variant of Modified GRF (1-29): the same growth-hormone-releasing-hormone backbone as the no-DAC form, extended at Lys30 with an Nε-3-maleimidopropionyl Drug Affinity Complex (DAC) linker. It is listed here strictly as an analytical reference and disambiguation entry — it is not sold, stocked, or certified by Lineará, and has no price or certificate of analysis. The data on this page is characterization only: molecular formula C165H269N47O46 and the values computed from it. It is a distinct chemical form from CJC-1295 (no DAC), which Lineará stocks and characterizes separately.
What is the molecular formula of CJC-1295 DAC?
CJC-1295 DAC has the molecular formula C165H269N47O46, giving an average molecular weight of 3647.20 g/mol and a monoisotopic mass of 3645.0155 Da.
What is the CAS number of CJC-1295 DAC?
The CAS Registry Number for CJC-1295 DAC is 446262-90-4. Its PubChem CID is 91971820, its FDA UNII is 62RC32V9N7, and its InChIKey is ZUQGTWKGESAQCD-ZGFIGYLBSA-N.
Is CJC-1295 DAC the same as CJC-1295 (no DAC)?
No. Albumin-binding long-acting variant of Modified GRF (1-29). The compound Lineará stocks is the no-DAC form (CJC-1295 / Mod GRF 1-29); this DAC variant is listed here for characterization and disambiguation only. The two are distinct chemical forms with different molecular formulas and masses.
Is CJC-1295 DAC a peptide?
Yes. CJC-1295 DAC is a peptide — a chain of amino-acid residues joined by peptide bonds, 30 residues in length. Its identity is defined by that sequence and its molecular mass.
How is CJC-1295 DAC stored and reconstituted?
As a research material, CJC-1295 DAC is typically handled as a lyophilized (freeze-dried) powder. It is kept desiccated and cold — commonly 2–8 °C for short periods and −20 °C for longer storage — and reconstituted in sterile or bacteriostatic water. This is storage and handling information only, not a use protocol.
Does Lineará sell CJC-1295 DAC?
No. CJC-1295 DAC is listed here only as an analytical reference and disambiguation entity. It is not part of the Lineará formulary, has no price or certificate of analysis, and is not offered for sale.
Is CJC-1295 DAC approved for human use?
No. CJC-1295 DAC is presented strictly as characterization reference data. It is not a drug, is not approved for any human or veterinary use, and must not be administered to humans or animals.

Data, tools & related references

Peptide fundamentals
What are peptides? — peptide bonds, structure & chemistry
→
Peptide chemistry glossary — defined terms
→
Analytical data & tools
CJC-1295 DAC molecular weight, m/z & pI
→
Peptide mass & m/z calculator
→
Open compound dataset (CSV · JSON)
→
Disambiguation
CJC-1295 (no DAC) — the form Lineará stocks
→
Research class
Secretagogue & Regulatory — research class
→

References

  1. PubChem — compound identity, structure & computed properties (CID 91971820). PubChem →
  2. CAS Registry Number 446262-90-4.
  3. FDA Global Substance Registration System — UNII 62RC32V9N7.
  4. Stocked form: CJC-1295 (no DAC) — structure, CAS & molecular weight.

Research professionals only

Reference data

This monograph is characterization reference data. Lineará does not sell, stock, or certify CJC-1295 DAC.

Browse Secretagogue & Regulatory researchHow to read a COA
áFor Research Use Only · Not for human or veterinary use · Not for diagnostic or therapeutic use

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