Thymulin
Thymulin is a synthetic nonapeptide corresponding to thymulin (serum thymic factor), H-pGlu-Ala-Lys-Ser-Gln-Gly-Gly-Ser-Asn-OH, a classical zinc-associated thymic nonapeptide first characterized by Bach and Dardenne — distinct from the Khavinson short-peptide line and from the bovine-thymus extract Thymalin.

Identity & structure
Primary sequence · 9 residues · N-terminal pyroglutamate (pGlu); metal-free nonapeptide form.
| Identity | |
|---|---|
| CAS | 63958-90-7 |
| PubChem CID | 3085284 |
| FDA UNII | 9H198D04WL |
| Also known as | Thymulin peptide, Serum thymic factor, FTS, Facteur thymique serique, Nonathymulin, Zinc-thymulin |
| Research class | Regenerative & Cytoprotective |
| Structure | |
| Molecular formula | C33H54N12O15 |
| InChIKey | LIFNDDBLJFPEAN-BPSSIEEOSA-N |
| Sequence | pGlu-Ala-Lys-Ser-Gln-Gly-Gly-Ser-Asn |
| Length | 9 residues |
| Analytical | |
| Average molecular weight | 858.86 g/mol |
| Monoisotopic mass | 858.3832 Da (computed) |
A nonapeptide with an N-terminal pyroglutamate, H-pGlu-Ala-Lys-Ser-Gln-Gly-Gly-Ser-Asn-OH (serum thymic factor, FTS). The formula and mass here are for the metal-free nonapeptide, C33H54N12O15, the CAS-63958-90-7 entity; thymulin proper is the zinc-BOUND complex of this same nonapeptide, and the zinc is a bound cofactor — NOT part of the covalent formula (cf. the GHK-Cu precedent). Identity is reconciled against PubChem CID 3085284: the stereo-defined InChIKey LIFNDDBLJFPEAN-BPSSIEEOSA-N matches the deposited record exactly (seven stereocentres, none unassigned). It is a defined synthetic nonapeptide from a classical thymic lineage (Bach and Dardenne), NOT a Khavinson short peptide, and must be kept distinct from Thymalin — a bovine-thymus polypeptide extract with which registries frequently, and wrongly, conflate it; Thymalin is therefore excluded from the synonyms. A computed 3D conformer is held pending the chemist sign-off.
Reference context
Thymulin is a synthetic nonapeptide corresponding to thymulin (serum thymic factor), H-pGlu-Ala-Lys-Ser-Gln-Gly-Gly-Ser-Asn-OH, a classical zinc-associated thymic nonapeptide first characterized by Bach and Dardenne — distinct from the Khavinson short-peptide line and from the bovine-thymus extract Thymalin. It is listed here strictly as an analytical reference entity — it is not sold, stocked, or certified by Lineará, and has no price or certificate of analysis. The data on this page is characterization only: molecular formula C33H54N12O15 and the values computed from it. No biological activity, mechanism, or use is described or implied.
Listed solely as a characterized analytical reference — no representation is made as to any biological effect. For Research Use Only — not for human or veterinary use.
How Thymulin is characterized
Identity rests on the molecular formula and mass. Electrospray mass spectrometry (ESI-MS) measures the mass-to-charge ratio of the intact molecule; the average and monoisotopic masses are computed from the verified formula and cross-check the composition. The residue sequence and the modifications noted above define the structure.
Frequently asked questions
What is Thymulin?
What is the amino-acid sequence of Thymulin?
What is the molecular formula of Thymulin?
What are the key chemical identifiers for Thymulin?
Is Thymulin a peptide?
How is Thymulin stored and reconstituted?
Does Lineará sell Thymulin?
Is Thymulin approved for human use?
Data, tools & related references
References
- PubChem — compound identity, structure & computed properties (CID 3085284). PubChem →
- CAS Registry Number 63958-90-7.
- FDA Global Substance Registration System — UNII 9H198D04WL.
Research professionals only
Reference data
This monograph is characterization reference data. Lineará does not sell, stock, or certify Thymulin.