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Regenerative & CytoprotectiveOpen access · public

Larazotide

Larazotide is a synthetic linear octapeptide, H-Gly-Gly-Val-Leu-Val-Gln-Pro-Gly-OH (GGVLVQPG), with free N- and C-termini and a central proline, carrying the development name AT-1001 and the INN larazotide.

CAS 258818-34-7Mol. weight 725.85 g/molResearch Use Only · reference
2D structure of Larazotide (PubChem CID 9810532)
2D structure via PubChem (CID 9810532). Public domain.
Computed 3D conformation (illustrative) · from the verified structure.

Identity & structure

G
G
V
L
V
Q
P
G

Primary sequence · 8 residues · Linear octapeptide (GGVLVQPG = H-Gly-Gly-Val-Leu-Val-Gln-Pro-Gly-OH) with free N- and C-termini and a central proline; free-peptide form (the acetate salt is a separate registry record)..

Larazotide — identity and specification
Identity
CAS258818-34-7
PubChem CID9810532
FDA UNIIZN3R5560ZV
Also known asAT-1001, AT1001, Larazotide peptide
Research classRegenerative & Cytoprotective
Structure
Molecular formulaC32H55N9O10
InChIKeyORFLZNAGUTZRLQ-ZMBVWFSWSA-N
SequenceGly-Gly-Val-Leu-Val-Gln-Pro-Gly
Length8 residues
Analytical
Average molecular weight725.85 g/mol
Monoisotopic mass725.4072 Da (computed)

A linear octapeptide, H-Gly-Gly-Val-Leu-Val-Gln-Pro-Gly-OH (single-letter GGVLVQPG), with free N- and C-termini — non-amidated and non-cyclic — glycine-rich with a central proline that constrains the backbone; the five stereocentres are all L (the three glycines are achiral). It carries the development name AT-1001 and the INN 'larazotide'. The identifiers here are the FREE-PEPTIDE record (CAS 258818-34-7, PubChem CID 9810532); the acetate salt used in most studies is the distinct CAS 881851-50-9 and is not the record published here. The stereo-defined InChIKey ORFLZNAGUTZRLQ-ZMBVWFSWSA-N was derived from the free-peptide SMILES and reconciled against PubChem CID 9810532 at build.

Reference context

Larazotide is a synthetic linear octapeptide, H-Gly-Gly-Val-Leu-Val-Gln-Pro-Gly-OH (GGVLVQPG), with free N- and C-termini and a central proline, carrying the development name AT-1001 and the INN larazotide. It is listed here strictly as an analytical reference entity — it is not sold, stocked, or certified by Lineará, and has no price or certificate of analysis. The data on this page is characterization only: molecular formula C32H55N9O10 and the values computed from it. No biological activity, mechanism, or use is described or implied.

Listed solely as a characterized analytical reference — no representation is made as to any biological effect. For Research Use Only — not for human or veterinary use.

How Larazotide is characterized

Identity rests on the molecular formula and mass. Electrospray mass spectrometry (ESI-MS) measures the mass-to-charge ratio of the intact molecule; the average and monoisotopic masses are computed from the verified formula and cross-check the composition. The residue sequence and the modifications noted above define the structure.

CompositionMolecular formula · 8-residue peptide
MassAverage & monoisotopic · ESI-MS
IdentityCAS · PubChem CID · UNII · InChIKey
Computed mass & m/z →How an HPLC trace is read →

Frequently asked questions

What is Larazotide?
Larazotide is a synthetic linear octapeptide, H-Gly-Gly-Val-Leu-Val-Gln-Pro-Gly-OH (GGVLVQPG), with free N- and C-termini and a central proline, carrying the development name AT-1001 and the INN larazotide. It is listed here strictly as an analytical reference entity — it is not sold, stocked, or certified by Lineará, and has no price or certificate of analysis. The data on this page is characterization only: molecular formula C32H55N9O10 and the values computed from it. No biological activity, mechanism, or use is described or implied.
What is the amino-acid sequence of Larazotide?
Larazotide has the sequence Gly-Gly-Val-Leu-Val-Gln-Pro-Gly. A linear octapeptide, H-Gly-Gly-Val-Leu-Val-Gln-Pro-Gly-OH (single-letter GGVLVQPG), with free N- and C-termini — non-amidated and non-cyclic — glycine-rich with a central proline that constrains the backbone; the five stereocentres are all L (the three glycines are achiral). It carries the development name AT-1001 and the INN 'larazotide'. The identifiers here are the FREE-PEPTIDE record (CAS 258818-34-7, PubChem CID 9810532); the acetate salt used in most studies is the distinct CAS 881851-50-9 and is not the record published here. The stereo-defined InChIKey ORFLZNAGUTZRLQ-ZMBVWFSWSA-N was derived from the free-peptide SMILES and reconciled against PubChem CID 9810532 at build.
What is the molecular formula of Larazotide?
Larazotide has the molecular formula C32H55N9O10, giving an average molecular weight of 725.85 g/mol and a computed monoisotopic mass of 725.4072 Da.
What are the key chemical identifiers for Larazotide?
The CAS Registry Number for Larazotide is 258818-34-7. Its PubChem CID is 9810532, its FDA UNII is ZN3R5560ZV, and its InChIKey is ORFLZNAGUTZRLQ-ZMBVWFSWSA-N.
Is Larazotide a peptide?
Yes. Larazotide is a peptide — a chain of amino-acid residues joined by peptide bonds, 8 residues in length. Its identity is defined by that sequence and its molecular mass.
How is Larazotide stored and reconstituted?
As a research material, Larazotide is typically handled as a lyophilized (freeze-dried) powder. It is kept desiccated and cold — commonly 2–8 °C for short periods and −20 °C for longer storage — and reconstituted in sterile or bacteriostatic water. This is storage and handling information only, not a use protocol.
Does Lineará sell Larazotide?
No. Larazotide is listed here only as an analytical reference entity. It is not part of the Lineará formulary, has no price or certificate of analysis, and is not offered for sale.
Is Larazotide approved for human use?
No. Larazotide is presented strictly as characterization reference data. It is not a drug, is not approved for any human or veterinary use, and must not be administered to humans or animals.

Data, tools & related references

Peptide fundamentals
What are peptides? — peptide bonds, structure & chemistry
→
Peptide chemistry glossary — defined terms
→
Analytical data & tools
Larazotide molecular weight, m/z & pI
→
Peptide mass & m/z calculator
→
Open compound dataset (CSV · JSON)
→
Research class
Regenerative & Cytoprotective — research class
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References

  1. PubChem — compound identity, structure & computed properties (CID 9810532). PubChem →
  2. CAS Registry Number 258818-34-7.
  3. FDA Global Substance Registration System — UNII ZN3R5560ZV.

Research professionals only

Reference data

This monograph is characterization reference data. Lineará does not sell, stock, or certify Larazotide.

Browse Regenerative & Cytoprotective researchHow to read a COA
áFor Research Use Only · Not for human or veterinary use · Not for diagnostic or therapeutic use

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