Regenerative & CytoprotectiveOpen access · public

ARA-290

ARA-290 is a synthetic 11-residue peptide from the erythropoietin helix-B domain, carrying an N-terminal pyroglutamate.

CAS 1208243-50-8Mol. weight 1257.32 g/molResearch Use Only

2D3D

2D structure via PubChem (CID 91810664). Public domain.

Computed 3D conformation (illustrative) · from the verified structure.

Identity & structure

Verified identifiers, sequence, and analytical properties — every value machine-readable and independently sourceable against PubChem.

pGlu

Primary sequence · 11 residues.

ARA-290 — identity and specification
Identity
CAS	1208243-50-8
PubChem CID	91810664
FDA UNII	9W5677JKDA
Also known as	ARA 290, ARA290, ARA-290 peptide, Cibinetide, pHBSP, pyroglutamate helix B surface peptide
Research class	Regenerative & Cytoprotective
Structure
Molecular formula	C51H84N16O21
InChIKey	WZTIQQBMSJTRBR-WYKNNRPVSA-N
Sequence	11-residue peptide (N-terminal pyroglutamate)
Length	11 residues
Analytical
Average molecular weight	1257.32 g/mol
Monoisotopic mass	1256.5997 Da
Form	Lyophilized powder
Solubility	Water-soluble
Storage	2–8 °C, desiccated

Where ARA-290 sits in its class

Cartalax333.30 KPV342.44 GHK-Cu403.93 Bronchogen446.45 Livagen461.47 Prostamax487.51 SS-31639.80 Larazotide725.85 Thymulin858.86

ARA-2901257.32

BPC-1571419.56 Thymosin Alpha-13108.32 LL-374493.34 TB-5004963.51 FOXO4-DRI5358.20

Molecular weight (g/mol) across the 15 characterized compounds in Regenerative & Cytoprotective. Compare all compounds →

Research context

ARA-290 is a synthetic 11-residue peptide from the erythropoietin helix-B domain, carrying an N-terminal pyroglutamate. Its molecular formula is C51H84N16O21, giving a molecular weight of 1257.32 g/mol. It is studied in tissue-protection research and is supplied as a characterized reference material.

Supplied solely as a characterized research material. No representation is made as to any biological effect. For Research Use Only — not for human or veterinary use.

All Regenerative & Cytoprotective compounds →

How ARA-290 is identified

Identity and purity are measured, not asserted. Electrospray mass spectrometry (ESI-MS) determines the mass-to-charge ratio of the intact molecule — an observed value matching the expected series above confirms the molecular formula. Reversed-phase HPLC separates the sample over time, and purity is read as arithmetic: the target peak’s area as a share of total peak area.

IdentityESI-MS · observed vs expected m/z

PurityRP-HPLC · peak area %

CompositionMolecular formula · residue count

Computed mass & m/z →How an HPLC trace is read →The lab record →

Handling & stability

Physical form, storage, and solubility as supplied. Handling guidance only — no use protocols.

Physical formLyophilized powder

Storage2–8 °C, desiccated

SolubilityWater-soluble

Length11 residues

Cold-chain handling →

Related compounds

Other compounds in this research class.

BPC-157

C62H98N16O22 · 1419.56

TB-500

C212H350N56O78S · 4963.51

GHK-Cu

C14H24CuN6O4 · 403.93

KPV

C16H30N4O4 · 342.44

Thymosin Alpha-1

C129H215N33O55 · 3108.32

C205H340N60O53 · 4493.34

C33H54N12O15 · 858.86

ACE-031

— · —

FOXO4-DRI

C228H388N86O64 · 5358.20

Show all 16 compounds →Show fewer

Frequently asked questions

What is ARA-290?

What is the molecular formula of ARA-290?

ARA-290 has the molecular formula C51H84N16O21, giving a molecular weight of 1257.32 g/mol. Its monoisotopic mass is 1256.5997 Da.

What is the CAS number of ARA-290?

The CAS Registry Number for ARA-290 is 1208243-50-8. Its InChIKey is WZTIQQBMSJTRBR-WYKNNRPVSA-N.

How is the identity of ARA-290 confirmed?

Identity is confirmed by electrospray mass spectrometry. The observed mass-to-charge ratio is compared against the expected series — for ARA-290, [M+H]⁺ is expected at m/z 1257.61. Purity is measured separately by reversed-phase HPLC as the target peak’s share of total peak area.

How should ARA-290 be stored?

ARA-290 is supplied as lyophilized powder and should be stored at 2–8 °C, desiccated. It is water-soluble.

Is ARA-290 a peptide?

Yes. ARA-290 is a peptide — a chain of amino-acid residues joined by peptide bonds, 11 residues in length. Its identity is defined by that sequence and its molecular mass.

Is ARA-290 approved for human use?

No. ARA-290 is supplied strictly for laboratory research use only. It is not a drug, is not approved by the FDA for any human or veterinary use, and must not be administered to humans or animals.

Research literature

Research literature — for reference only

Curated peer-reviewed references indexing the identity, characterization, and analytical-method literature for ARA-290, from the U.S. National Library of Medicine (PubMed). Listed as neutral citations only — no findings, conclusions, or use are stated or implied.

Simplifying and expanding the screening for peptides <2 kDa by direct urine injection, liquid chromatography, and ion mobility mass spectrometry.
Thomas A, Görgens C, Guddat S, Thieme D, Dellanna F, Schänzer W, et al.Journal of separation science2016
Detecting peptidic drugs, drug candidates and analogs in sports doping: current status and future directions.
Thevis M, Thomas A, Schänzer WExpert review of proteomics2014

References

PubChem — compound identity, structure & computed properties (CID 91810664). PubChem →
CAS Registry Number 1208243-50-8.
FDA Global Substance Registration System — UNII 9W5677JKDA.

Research professionals only

ARA-290 — from the record to the bench

The monograph and every lot certificate stay public. Pricing and ordering open for verified research professionals.

View ARA-290 in the formulary The certificate library

áFor Research Use Only · Not for human or veterinary use · Not for diagnostic or therapeutic use