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Regenerative & CytoprotectiveOpen access · public

KPV

KPV is a synthetic tripeptide, Lys-Pro-Val, corresponding to the C-terminal fragment of α-MSH, with the molecular formula C16H30N4O4 and a molecular weight of 342.44 g/mol.

CAS 67727-97-3Mol. weight 342.44 g/molResearch Use Only
2D structure of KPV (PubChem CID 125672)
2D structure via PubChem (CID 125672). Public domain.
Interactive 3D conformer via PubChem (CID 125672). Computed structure · public domain.

Identity & structure

Verified identifiers, sequence, and analytical properties — every value machine-readable and independently sourceable against PubChem.

K
P
V

Primary sequence · 3 residues.

KPV — identity and specification
Identity
CAS67727-97-3
PubChem CID125672
Also known asKPV peptide, Lys-Pro-Val, L-Lysyl-L-prolyl-L-valine, alpha-MSH (11-13), MSH (11-13), ACTH-(11-13)
Research classRegenerative & Cytoprotective
Structure
Molecular formulaC16H30N4O4
InChIKeyYSPZCHGIWAQVKQ-AVGNSLFASA-N
SequenceLys-Pro-Val
Length3 residues
Analytical
Average molecular weight342.44 g/mol
Monoisotopic mass342.2267 Da
FormLyophilized powder
SolubilityWater-soluble
Storage2–8 °C, desiccated

Research context

KPV is a synthetic tripeptide, Lys-Pro-Val, corresponding to the C-terminal fragment of α-MSH, with the molecular formula C16H30N4O4 and a molecular weight of 342.44 g/mol. It is studied in cytoprotection and inflammation research models and is supplied as a characterized reference material.

Supplied solely as a characterized research material. No representation is made as to any biological effect. For Research Use Only — not for human or veterinary use.

How KPV is identified

Identity and purity are measured, not asserted. Electrospray mass spectrometry (ESI-MS) determines the mass-to-charge ratio of the intact molecule — an observed value matching the expected series above confirms the molecular formula. Reversed-phase HPLC separates the sample over time, and purity is read as arithmetic: the target peak’s area as a share of total peak area.

IdentityESI-MS · observed vs expected m/z
PurityRP-HPLC · peak area %
CompositionMolecular formula · residue count

Handling & stability

Physical form, storage, and solubility as supplied. Handling guidance only — no use protocols.

Physical formLyophilized powder
Storage2–8 °C, desiccated
SolubilityWater-soluble
Length3 residues

Related compounds

Other compounds in this research class.

Frequently asked questions

What is KPV?
KPV is a synthetic tripeptide, Lys-Pro-Val, corresponding to the C-terminal fragment of α-MSH, with the molecular formula C16H30N4O4 and a molecular weight of 342.44 g/mol. It is studied in cytoprotection and inflammation research models and is supplied as a characterized reference material.
What is the molecular formula of KPV?
KPV has the molecular formula C16H30N4O4, giving a molecular weight of 342.44 g/mol. Its monoisotopic mass is 342.2267 Da.
What is the CAS number of KPV?
The CAS Registry Number for KPV is 67727-97-3. Its InChIKey is YSPZCHGIWAQVKQ-AVGNSLFASA-N.
How is the identity of KPV confirmed?
Identity is confirmed by electrospray mass spectrometry. The observed mass-to-charge ratio is compared against the expected series — for KPV, [M+H]⁺ is expected at m/z 343.23. Purity is measured separately by reversed-phase HPLC as the target peak’s share of total peak area.
How should KPV be stored?
KPV is supplied as lyophilized powder and should be stored at 2–8 °C, desiccated. It is water-soluble.
Is KPV a peptide?
Yes. KPV is a peptide — a chain of amino-acid residues joined by peptide bonds, 3 residues in length. Its identity is defined by that sequence and its molecular mass.
Is KPV approved for human use?
No. KPV is supplied strictly for laboratory research use only. It is not a drug, is not approved by the FDA for any human or veterinary use, and must not be administered to humans or animals.

Data, tools & certificates

Research literature

Research literature — for reference only

Curated peer-reviewed references indexing the identity, characterization, and analytical-method literature for KPV, from the U.S. National Library of Medicine (PubMed). Listed as neutral citations only — no findings, conclusions, or use are stated or implied.

  1. Stability-indicating HPLC assay for lysine-proline-valine (KPV) in aqueous solutions and skin homogenates.
    Pawar KR, Mulabagal V, Smith F, Kolli CS, Rangari VK, Babu RJBiomedical chromatography : BMC2015

References

  1. PubChem — compound identity, structure & computed properties (CID 125672). PubChem →
  2. CAS Registry Number 67727-97-3.

Research professionals only

KPV — from the record to the bench

The monograph and every lot certificate stay public. Pricing and ordering open for verified research professionals.

áFor Research Use Only · Not for human or veterinary use · Not for diagnostic or therapeutic use