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Regenerative & CytoprotectiveOpen access · public

GHK-Cu

GHK-Cu is a copper(II)-binding tripeptide complex — the tripeptide glycyl-L-histidyl-L-lysine coordinated to a copper(II) ion — with the molecular formula C14H24CuN6O4 and a molecular weight of 403.93 g/mol.

GHK-Cu is a tripeptide–copper(II) complex, commonly called a copper peptide: the tripeptide glycyl-L-histidyl-L-lysine coordinated to a copper(II) ion.

CAS 49557-75-7Mol. weight 403.93 g/molResearch Use Only
2D structure of GHK-Cu (PubChem CID 175761262)
2D structure via PubChem (CID 175761262). Public domain.
Computed 3D conformation (illustrative) · from the verified structure.

Identity & structure

Verified identifiers, sequence, and analytical properties — every value machine-readable and independently sourceable against PubChem.

G
H
K

Primary sequence · 3 residues · Cu(II) complex — the copper is coordinated, not covalently bonded.

GHK-Cu — identity and specification
Identity
CAS49557-75-7
PubChem CID175761262
FDA UNII6BJQ43T1I9
Also known asGHK Cu, GHKCu, Copper peptide, GHK copper peptide, Copper tripeptide-1, Copper peptide GHK-Cu, Glycyl-L-histidyl-L-lysine copper
Research classRegenerative & Cytoprotective
Structure
Molecular formulaC14H24CuN6O4
InChIKeyNZWIFMYRRCMYMN-ACMTZBLWSA-N
SequenceGly-His-Lys · Cu(II)
Length3 residues + Cu
Analytical
Average molecular weight403.93 g/mol
Monoisotopic mass403.1144 Da
FormLyophilized powder
SolubilityWater-soluble
Storage2–8 °C, desiccated

Research context

GHK-Cu is a copper(II)-binding tripeptide complex — the tripeptide glycyl-L-histidyl-L-lysine coordinated to a copper(II) ion — with the molecular formula C14H24CuN6O4 and a molecular weight of 403.93 g/mol. It is studied in matrix-biology and cytoprotection research and is supplied as a characterized reference material.

Supplied solely as a characterized research material. No representation is made as to any biological effect. For Research Use Only — not for human or veterinary use.

How GHK-Cu is identified

Identity and purity are measured, not asserted. Electrospray mass spectrometry (ESI-MS) determines the mass-to-charge ratio of the intact molecule — an observed value matching the expected series above confirms the molecular formula. Reversed-phase HPLC separates the sample over time, and purity is read as arithmetic: the target peak’s area as a share of total peak area.

IdentityESI-MS · observed vs expected m/z
PurityRP-HPLC · peak area %
CompositionMolecular formula · residue count

Handling & stability

Physical form, storage, and solubility as supplied. Handling guidance only — no use protocols.

Physical formLyophilized powder
Storage2–8 °C, desiccated
SolubilityWater-soluble
Length3 residues + Cu

Related compounds

Other compounds in this research class.

Frequently asked questions

What is GHK-Cu?
GHK-Cu is a copper(II)-binding tripeptide complex — the tripeptide glycyl-L-histidyl-L-lysine coordinated to a copper(II) ion — with the molecular formula C14H24CuN6O4 and a molecular weight of 403.93 g/mol. It is studied in matrix-biology and cytoprotection research and is supplied as a characterized reference material.
Is GHK-Cu a peptide?
GHK-Cu is a tripeptide–copper(II) complex, commonly called a copper peptide: the tripeptide glycyl-L-histidyl-L-lysine coordinated to a copper(II) ion.
What is the molecular formula of GHK-Cu?
GHK-Cu has the molecular formula C14H24CuN6O4, giving a molecular weight of 403.93 g/mol. Its monoisotopic mass is 403.1144 Da.
What is the CAS number of GHK-Cu?
The CAS Registry Number for GHK-Cu is 49557-75-7. Its InChIKey is NZWIFMYRRCMYMN-ACMTZBLWSA-N.
How is the identity of GHK-Cu confirmed?
Identity is confirmed by electrospray mass spectrometry. The observed mass-to-charge ratio is compared against the expected series — for GHK-Cu, [M+H]⁺ is expected at m/z 404.12. Purity is measured separately by reversed-phase HPLC as the target peak’s share of total peak area.
How should GHK-Cu be stored?
GHK-Cu is supplied as lyophilized powder and should be stored at 2–8 °C, desiccated. It is water-soluble.
Is GHK-Cu approved for human use?
No. GHK-Cu is supplied strictly for laboratory research use only. It is not a drug, is not approved by the FDA for any human or veterinary use, and must not be administered to humans or animals.

Data, tools & certificates

References

  1. PubChem — compound identity, structure & computed properties (CID 175761262). PubChem →
  2. CAS Registry Number 49557-75-7.
  3. FDA Global Substance Registration System — UNII 6BJQ43T1I9.

Research professionals only

GHK-Cu — from the record to the bench

The monograph and every lot certificate stay public. Pricing and ordering open for verified research professionals.

áFor Research Use Only · Not for human or veterinary use · Not for diagnostic or therapeutic use