SNAP-8
SNAP-8 is a synthetic, N-acetylated and C-terminally amidated octapeptide, Ac-Glu-Glu-Met-Gln-Arg-Arg-Ala-Asp-NH2 (Ac-EEMQRRAD-NH2), that extends the acetyl-hexapeptide (argireline) motif by two residues.

Identity & structure
Primary sequence · 8 residues · N-terminal Acetyl · C-terminal amide · Octapeptide amide (Ac-EEMQRRAD-NH2): eight L-amino acids, N-acetylated and C-terminally amidated. Extends the acetyl-hexapeptide (argireline) motif Ac-EEMQRR- by the two residues Ala-Asp..
| Identity | |
|---|---|
| CAS | 868844-74-0 |
| Also known as | Acetyl Octapeptide-3, Acetyl Octapeptide-1, Acetyl Glutamyl Heptapeptide-1, Octapeptide-3, SNAP 8, SNAP-8 peptide |
| Research class | Signaling & Neuroactive |
| Structure | |
| Molecular formula | C41H70N16O16S |
| Sequence | Ac-Glu-Glu-Met-Gln-Arg-Arg-Ala-Asp-NH2 |
| Length | 8 residues |
| Analytical | |
| Average molecular weight | 1075.17 g/mol |
| Monoisotopic mass | 1074.4876 Da (computed) |
SNAP-8 has the sequence Ac-Glu-Glu-Met-Gln-Arg-Arg-Ala-Asp-NH2 (single-letter Ac-EEMQRRAD-NH2): eight L-amino acids capped with an N-terminal acetyl group and a C-terminal primary amide. Its lone methionine contributes the single sulfur atom, and the sequence computes exactly to the molecular formula C41H70N16O16S (average mass 1075.17 g/mol). No PubChem CID is published here: the record catalogued as "Acetyl octapeptide-3" (CID 71587832) stores a different formula, C42H72N16O15S, which does not reconcile with this sequence, so it is not shipped as a verified identifier and is flagged for chemist review as a likely record error. No InChIKey or FDA UNII is asserted for the same reason — neither could be machine-verified against a reconciled record.
Reference context
SNAP-8 is a synthetic, N-acetylated and C-terminally amidated octapeptide, Ac-Glu-Glu-Met-Gln-Arg-Arg-Ala-Asp-NH2 (Ac-EEMQRRAD-NH2), that extends the acetyl-hexapeptide (argireline) motif by two residues. It is listed here strictly as an analytical reference entity — it is not sold, stocked, or certified by Lineará, and has no price or certificate of analysis. The data on this page is characterization only: molecular formula C41H70N16O16S and the values computed from it. No biological activity, mechanism, or use is described or implied.
Listed solely as a characterized analytical reference — no representation is made as to any biological effect. For Research Use Only — not for human or veterinary use.
How SNAP-8 is characterized
Identity rests on the molecular formula and mass. Electrospray mass spectrometry (ESI-MS) measures the mass-to-charge ratio of the intact molecule; the average and monoisotopic masses are computed from the verified formula and cross-check the composition. The residue sequence and the modifications noted above define the structure.
Frequently asked questions
What is SNAP-8?
What is the amino-acid sequence of SNAP-8?
What is the molecular formula of SNAP-8?
What are the key chemical identifiers for SNAP-8?
Is SNAP-8 a peptide?
How is SNAP-8 stored and reconstituted?
Does Lineará sell SNAP-8?
Is SNAP-8 approved for human use?
Data, tools & related references
References
- CAS Registry Number 868844-74-0.
Research professionals only
Reference data
This monograph is characterization reference data. Lineará does not sell, stock, or certify SNAP-8.