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Signaling & NeuroactiveOpen access · public

PT-141

PT-141 is a synthetic cyclic heptapeptide and melanocortin-receptor analog, with the molecular formula C50H68N14O10 and a molecular weight of 1025.18 g/mol.

CAS 189691-06-3Mol. weight 1025.18 g/molResearch Use Only
2D structure of PT-141 (PubChem CID 9941379)
2D structure via PubChem (CID 9941379). Public domain.
Computed 3D conformation (illustrative) · from the verified structure.

Identity & structure

Verified identifiers, sequence, and analytical properties — every value machine-readable and independently sourceable against PubChem.

Ac–
Nle
D
H
D-Phe
R
W
K

Primary sequence · 7 residues · N-terminal Acetyl · lactam bridge (cyclic) D2–K7.

PT-141 — identity and specification
Identity
CAS189691-06-3
PubChem CID9941379
FDA UNII6Y24O4F92S
Also known asPT 141, PT141, PT 141 peptide, Bremelanotide
Research classSignaling & Neuroactive
Structure
Molecular formulaC50H68N14O10
InChIKeyFFHBJDQSGDNCIV-MFVUMRCOSA-N
Sequencecyclic 7-residue
Length7 residues
Analytical
Average molecular weight1025.18 g/mol
Monoisotopic mass1024.5243 Da
FormLyophilized powder
SolubilityWater-soluble
Storage2–8 °C, desiccated

Research context

PT-141 is a synthetic cyclic heptapeptide and melanocortin-receptor analog, with the molecular formula C50H68N14O10 and a molecular weight of 1025.18 g/mol. It is studied in signaling research and is supplied as a characterized reference material, with identity confirmed by mass spectrometry.

Supplied solely as a characterized research material. No representation is made as to any biological effect. For Research Use Only — not for human or veterinary use.

How PT-141 is identified

Identity and purity are measured, not asserted. Electrospray mass spectrometry (ESI-MS) determines the mass-to-charge ratio of the intact molecule — an observed value matching the expected series above confirms the molecular formula. Reversed-phase HPLC separates the sample over time, and purity is read as arithmetic: the target peak’s area as a share of total peak area.

IdentityESI-MS · observed vs expected m/z
PurityRP-HPLC · peak area %
CompositionMolecular formula · residue count

Handling & stability

Physical form, storage, and solubility as supplied. Handling guidance only — no use protocols.

Physical formLyophilized powder
Storage2–8 °C, desiccated
SolubilityWater-soluble
Length7 residues

Related compounds

Other compounds in this research class.

Frequently asked questions

What is PT-141?
PT-141 is a synthetic cyclic heptapeptide and melanocortin-receptor analog, with the molecular formula C50H68N14O10 and a molecular weight of 1025.18 g/mol. It is studied in signaling research and is supplied as a characterized reference material, with identity confirmed by mass spectrometry.
What is the molecular formula of PT-141?
PT-141 has the molecular formula C50H68N14O10, giving a molecular weight of 1025.18 g/mol. Its monoisotopic mass is 1024.5243 Da.
What is the CAS number of PT-141?
The CAS Registry Number for PT-141 is 189691-06-3. Its InChIKey is FFHBJDQSGDNCIV-MFVUMRCOSA-N.
How is the identity of PT-141 confirmed?
Identity is confirmed by electrospray mass spectrometry. The observed mass-to-charge ratio is compared against the expected series — for PT-141, [M+H]⁺ is expected at m/z 1025.53. Purity is measured separately by reversed-phase HPLC as the target peak’s share of total peak area.
How should PT-141 be stored?
PT-141 is supplied as lyophilized powder and should be stored at 2–8 °C, desiccated. It is water-soluble.
Is PT-141 a peptide?
Yes. PT-141 is a peptide — a chain of amino-acid residues joined by peptide bonds, 7 residues in length. Its identity is defined by that sequence and its molecular mass.
Is PT-141 approved for human use?
No. PT-141 is supplied strictly for laboratory research use only. It is not a drug, is not approved by the FDA for any human or veterinary use, and must not be administered to humans or animals.

Data, tools & certificates

References

  1. PubChem — compound identity, structure & computed properties (CID 9941379). PubChem →
  2. CAS Registry Number 189691-06-3.
  3. FDA Global Substance Registration System — UNII 6Y24O4F92S.

Research professionals only

PT-141 — from the record to the bench

The monograph and every lot certificate stay public. Pricing and ordering open for verified research professionals.

áFor Research Use Only · Not for human or veterinary use · Not for diagnostic or therapeutic use