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Signaling & NeuroactiveOpen access · public

MT-1 (Melanotan 1)

MT-1 (Melanotan 1) is a synthetic 13-residue α-MSH analog with the molecular formula C78H111N21O19 and a molecular weight of 1646.87 g/mol.

CAS 75921-69-6Mol. weight 1646.87 g/molResearch Use Only
2D structure of MT-1 (Melanotan 1) (PubChem CID 16154396)
2D structure via PubChem (CID 16154396). Public domain.
Computed 3D conformation (illustrative) · from the verified structure.

Identity & structure

Verified identifiers, sequence, and analytical properties — every value machine-readable and independently sourceable against PubChem.

Ac–
S
Y
S
Nle
E
H
D-Phe
R
W
G
K
P
V
–NH₂

Primary sequence · 13 residues · N-terminal Acetyl · C-terminal amide.

MT-1 (Melanotan 1) — identity and specification
Identity
CAS75921-69-6
PubChem CID16154396
FDA UNIIQW68W3J66U
Also known asMelanotan 1, MT-1, MT 1, Melanotan 1 peptide, Afamelanotide, Melanotan I, CUV1647, CUV-1647, NDP-alpha-MSH, [Nle4,D-Phe7]-alpha-MSH
Research classSignaling & Neuroactive
Structure
Molecular formulaC78H111N21O19
InChIKeyUAHFGYDRQSXQEB-LEBBXHLNSA-N
Sequence13-residue analog
Length13 residues
Analytical
Average molecular weight1646.87 g/mol
Monoisotopic mass1645.8365 Da
FormLyophilized powder
SolubilityWater-soluble
Storage2–8 °C, desiccated

Research context

MT-1 (Melanotan 1) is a synthetic 13-residue α-MSH analog with the molecular formula C78H111N21O19 and a molecular weight of 1646.87 g/mol. It is studied in melanocortin-signaling research as a characterized reference material and is verified by reversed-phase HPLC and mass spectrometry.

Supplied solely as a characterized research material. No representation is made as to any biological effect. For Research Use Only — not for human or veterinary use.

How MT-1 (Melanotan 1) is identified

Identity and purity are measured, not asserted. Electrospray mass spectrometry (ESI-MS) determines the mass-to-charge ratio of the intact molecule — an observed value matching the expected series above confirms the molecular formula. Reversed-phase HPLC separates the sample over time, and purity is read as arithmetic: the target peak’s area as a share of total peak area.

IdentityESI-MS · observed vs expected m/z
PurityRP-HPLC · peak area %
CompositionMolecular formula · residue count

Handling & stability

Physical form, storage, and solubility as supplied. Handling guidance only — no use protocols.

Physical formLyophilized powder
Storage2–8 °C, desiccated
SolubilityWater-soluble
Length13 residues

Related compounds

Other compounds in this research class.

Frequently asked questions

What is MT-1 (Melanotan 1)?
MT-1 (Melanotan 1) is a synthetic 13-residue α-MSH analog with the molecular formula C78H111N21O19 and a molecular weight of 1646.87 g/mol. It is studied in melanocortin-signaling research as a characterized reference material and is verified by reversed-phase HPLC and mass spectrometry.
What is the molecular formula of MT-1 (Melanotan 1)?
MT-1 (Melanotan 1) has the molecular formula C78H111N21O19, giving a molecular weight of 1646.87 g/mol. Its monoisotopic mass is 1645.8365 Da.
What is the CAS number of MT-1 (Melanotan 1)?
The CAS Registry Number for MT-1 (Melanotan 1) is 75921-69-6. Its InChIKey is UAHFGYDRQSXQEB-LEBBXHLNSA-N.
How is the identity of MT-1 (Melanotan 1) confirmed?
Identity is confirmed by electrospray mass spectrometry. The observed mass-to-charge ratio is compared against the expected series — for MT-1 (Melanotan 1), [M+H]⁺ is expected at m/z 1646.84. Purity is measured separately by reversed-phase HPLC as the target peak’s share of total peak area.
How should MT-1 (Melanotan 1) be stored?
MT-1 (Melanotan 1) is supplied as lyophilized powder and should be stored at 2–8 °C, desiccated. It is water-soluble.
Is MT-1 (Melanotan 1) a peptide?
Yes. MT-1 (Melanotan 1) is a peptide — a chain of amino-acid residues joined by peptide bonds, 13 residues in length. Its identity is defined by that sequence and its molecular mass.
Is MT-1 (Melanotan 1) approved for human use?
No. MT-1 (Melanotan 1) is supplied strictly for laboratory research use only. It is not a drug, is not approved by the FDA for any human or veterinary use, and must not be administered to humans or animals.

Data, tools & certificates

References

  1. PubChem — compound identity, structure & computed properties (CID 16154396). PubChem →
  2. CAS Registry Number 75921-69-6.
  3. FDA Global Substance Registration System — UNII QW68W3J66U.

Research professionals only

MT-1 (Melanotan 1) — from the record to the bench

The monograph and every lot certificate stay public. Pricing and ordering open for verified research professionals.

áFor Research Use Only · Not for human or veterinary use · Not for diagnostic or therapeutic use