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Signaling & NeuroactiveOpen access · public

Semax

Semax is a synthetic heptapeptide, sequence MEHFPGP, related to a fragment of ACTH, with the molecular formula C37H51N9O10S and a molecular weight of 813.93 g/mol.

CAS 80714-61-0Mol. weight 813.93 g/molResearch Use Only
2D structure of Semax (PubChem CID 9811102)
2D structure via PubChem (CID 9811102). Public domain.
Computed 3D conformation (illustrative) · from the verified structure.

Identity & structure

Verified identifiers, sequence, and analytical properties — every value machine-readable and independently sourceable against PubChem.

M
E
H
F
P
G
P

Primary sequence · 7 residues.

Semax — identity and specification
Identity
CAS80714-61-0
PubChem CID9811102
FDA UNIII5FAL2585H
Also known asSemax peptide, ACTH (4-7), Pro-Gly-Pro-
Research classSignaling & Neuroactive
Structure
Molecular formulaC37H51N9O10S
InChIKeyAFEHBIGDWIGTEH-AQRCPPRCSA-N
SequenceMEHFPGP
Length7 residues
Analytical
Average molecular weight813.93 g/mol
Monoisotopic mass813.348 Da
FormLyophilized powder
SolubilityWater-soluble
Storage2–8 °C, desiccated

Research context

Semax is a synthetic heptapeptide, sequence MEHFPGP, related to a fragment of ACTH, with the molecular formula C37H51N9O10S and a molecular weight of 813.93 g/mol. It is studied in neuromodulation research and is supplied as a stable, synthetically accessible reference material.

Supplied solely as a characterized research material. No representation is made as to any biological effect. For Research Use Only — not for human or veterinary use.

How Semax is identified

Identity and purity are measured, not asserted. Electrospray mass spectrometry (ESI-MS) determines the mass-to-charge ratio of the intact molecule — an observed value matching the expected series above confirms the molecular formula. Reversed-phase HPLC separates the sample over time, and purity is read as arithmetic: the target peak’s area as a share of total peak area.

IdentityESI-MS · observed vs expected m/z
PurityRP-HPLC · peak area %
CompositionMolecular formula · residue count

Handling & stability

Physical form, storage, and solubility as supplied. Handling guidance only — no use protocols.

Physical formLyophilized powder
Storage2–8 °C, desiccated
SolubilityWater-soluble
Length7 residues

Related compounds

Other compounds in this research class.

Frequently asked questions

What is Semax?
Semax is a synthetic heptapeptide, sequence MEHFPGP, related to a fragment of ACTH, with the molecular formula C37H51N9O10S and a molecular weight of 813.93 g/mol. It is studied in neuromodulation research and is supplied as a stable, synthetically accessible reference material.
What is the molecular formula of Semax?
Semax has the molecular formula C37H51N9O10S, giving a molecular weight of 813.93 g/mol. Its monoisotopic mass is 813.348 Da.
What is the CAS number of Semax?
The CAS Registry Number for Semax is 80714-61-0. Its InChIKey is AFEHBIGDWIGTEH-AQRCPPRCSA-N.
How is the identity of Semax confirmed?
Identity is confirmed by electrospray mass spectrometry. The observed mass-to-charge ratio is compared against the expected series — for Semax, [M+H]⁺ is expected at m/z 814.36. Purity is measured separately by reversed-phase HPLC as the target peak’s share of total peak area.
How should Semax be stored?
Semax is supplied as lyophilized powder and should be stored at 2–8 °C, desiccated. It is water-soluble.
Is Semax a peptide?
Yes. Semax is a peptide — a chain of amino-acid residues joined by peptide bonds, 7 residues in length. Its identity is defined by that sequence and its molecular mass.
Is Semax approved for human use?
No. Semax is supplied strictly for laboratory research use only. It is not a drug, is not approved by the FDA for any human or veterinary use, and must not be administered to humans or animals.

Data, tools & certificates

References

  1. PubChem — compound identity, structure & computed properties (CID 9811102). PubChem →
  2. CAS Registry Number 80714-61-0.
  3. FDA Global Substance Registration System — UNII I5FAL2585H.

Research professionals only

Semax — from the record to the bench

The monograph and every lot certificate stay public. Pricing and ordering open for verified research professionals.

áFor Research Use Only · Not for human or veterinary use · Not for diagnostic or therapeutic use