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Regenerative & CytoprotectiveOpen access · public

TB-500 Fragment (Ac-LKKTETQ)

TB-500 Fragment (Ac-LKKTETQ) is a short N-acetyl heptapeptide (Ac-Leu-Lys-Lys-Thr-Glu-Thr-Gln-OH) corresponding to residues 17–23 of thymosin β4 — the actin-binding motif region, sometimes marketed under the "TB-500" name.

CAS 885340-08-9Mol. weight 889.02 g/molResearch Use Only · reference
2D structure of TB-500 Fragment (Ac-LKKTETQ) (PubChem CID 62707662)
2D structure via PubChem (CID 62707662). Public domain.
Computed 3D conformation (illustrative) · from the verified structure.

Identity & structure

Ac–
L
K
K
T
E
T
Q

Primary sequence · 7 residues · N-terminal Acetyl · N-acetylated free-acid heptapeptide corresponding to residues 17–23 of thymosin β4.

TB-500 Fragment (Ac-LKKTETQ) — identity and specification
Identity
CAS885340-08-9
PubChem CID62707662
FDA UNIIQHK6Z47GTG
Also known asTB-500 fragment, TB 500 fragment, Ac-LKKTETQ, Thymosin β4 (17-23), Thymosin beta-4 fragment, TB-500 Fragment peptide
Research classRegenerative & Cytoprotective
Structure
Molecular formulaC38H68N10O14
InChIKeyADKDNDYYIZUVCZ-ZQNQAVPYSA-N
SequenceAc-Leu-Lys-Lys-Thr-Glu-Thr-Gln-OH
Length7 residues
Analytical
Average molecular weight889.02 g/mol
Monoisotopic mass888.4916 Da

The N-acetylated, free-acid heptapeptide corresponding to residues 17–23 of thymosin β4 (the LKKTET actin-binding motif region). This is a short fragment — not the full-length protein.

Disambiguation

TB-500 Fragment (Ac-LKKTETQ) is a short N-acetyl heptapeptide (Ac-Leu-Lys-Lys-Thr-Glu-Thr-Gln-OH) corresponding to residues 17–23 of thymosin β4 — the actin-binding motif region, sometimes marketed under the "TB-500" name. It is listed here strictly as an analytical reference and disambiguation entry — it is not sold, stocked, or certified by Lineará, and has no price or certificate of analysis. The data on this page is characterization only: molecular formula C38H68N10O14 and the values computed from it. It is a distinct chemical form from TB-500 (full-length thymosin β4), which Lineará stocks and characterizes separately.

Not to be confused with TB-500 (full-length thymosin β4). A short actin-binding fragment sometimes marketed as "TB-500". The compound Lineará stocks under that name is full-length thymosin β4; this 7-residue fragment is listed here for characterization and disambiguation only. Listed solely as a characterized analytical reference — no representation is made as to any biological effect. For Research Use Only — not for human or veterinary use.

View TB-500 (full-length thymosin β4) →

How TB-500 Fragment (Ac-LKKTETQ) is characterized

Identity rests on the molecular formula and mass. Electrospray mass spectrometry (ESI-MS) measures the mass-to-charge ratio of the intact molecule; the average and monoisotopic masses cross-check the composition. The residue sequence and the modifications noted above define the structure.

CompositionMolecular formula · 7-residue peptide
MassAverage & monoisotopic · ESI-MS
IdentityCAS · PubChem CID · UNII · InChIKey
Computed mass & m/z →How an HPLC trace is read →

Frequently asked questions

What is TB-500 Fragment (Ac-LKKTETQ)?
TB-500 Fragment (Ac-LKKTETQ) is a short N-acetyl heptapeptide (Ac-Leu-Lys-Lys-Thr-Glu-Thr-Gln-OH) corresponding to residues 17–23 of thymosin β4 — the actin-binding motif region, sometimes marketed under the "TB-500" name. It is listed here strictly as an analytical reference and disambiguation entry — it is not sold, stocked, or certified by Lineará, and has no price or certificate of analysis. The data on this page is characterization only: molecular formula C38H68N10O14 and the values computed from it. It is a distinct chemical form from TB-500 (full-length thymosin β4), which Lineará stocks and characterizes separately.
What is the molecular formula of TB-500 Fragment (Ac-LKKTETQ)?
TB-500 Fragment (Ac-LKKTETQ) has the molecular formula C38H68N10O14, giving an average molecular weight of 889.02 g/mol and a monoisotopic mass of 888.4916 Da.
What is the CAS number of TB-500 Fragment (Ac-LKKTETQ)?
The CAS Registry Number for TB-500 Fragment (Ac-LKKTETQ) is 885340-08-9. Its PubChem CID is 62707662, its FDA UNII is QHK6Z47GTG, and its InChIKey is ADKDNDYYIZUVCZ-ZQNQAVPYSA-N.
Is TB-500 Fragment (Ac-LKKTETQ) the same as TB-500 (full-length thymosin β4)?
No. A short actin-binding fragment sometimes marketed as "TB-500". The compound Lineará stocks under that name is full-length thymosin β4; this 7-residue fragment is listed here for characterization and disambiguation only. The two are distinct chemical forms with different molecular formulas and masses.
Is TB-500 Fragment (Ac-LKKTETQ) a peptide?
Yes. TB-500 Fragment (Ac-LKKTETQ) is a peptide — a chain of amino-acid residues joined by peptide bonds, 7 residues in length. Its identity is defined by that sequence and its molecular mass.
How is TB-500 Fragment (Ac-LKKTETQ) stored and reconstituted?
As a research material, TB-500 Fragment (Ac-LKKTETQ) is typically handled as a lyophilized (freeze-dried) powder. It is kept desiccated and cold — commonly 2–8 °C for short periods and −20 °C for longer storage — and reconstituted in sterile or bacteriostatic water. This is storage and handling information only, not a use protocol.
Does Lineará sell TB-500 Fragment (Ac-LKKTETQ)?
No. TB-500 Fragment (Ac-LKKTETQ) is listed here only as an analytical reference and disambiguation entity. It is not part of the Lineará formulary, has no price or certificate of analysis, and is not offered for sale.
Is TB-500 Fragment (Ac-LKKTETQ) approved for human use?
No. TB-500 Fragment (Ac-LKKTETQ) is presented strictly as characterization reference data. It is not a drug, is not approved for any human or veterinary use, and must not be administered to humans or animals.

Data, tools & related references

Peptide fundamentals
What are peptides? — peptide bonds, structure & chemistry
→
Peptide chemistry glossary — defined terms
→
Analytical data & tools
TB-500 Fragment (Ac-LKKTETQ) molecular weight, m/z & pI
→
Peptide mass & m/z calculator
→
Open compound dataset (CSV · JSON)
→
Disambiguation
TB-500 (full-length thymosin β4) — the form Lineará stocks
→
Research class
Regenerative & Cytoprotective — research class
→

References

  1. PubChem — compound identity, structure & computed properties (CID 62707662). PubChem →
  2. CAS Registry Number 885340-08-9.
  3. FDA Global Substance Registration System — UNII QHK6Z47GTG.
  4. Stocked form: TB-500 (full-length thymosin β4) — structure, CAS & molecular weight.

Research professionals only

Reference data

This monograph is characterization reference data. Lineará does not sell, stock, or certify TB-500 Fragment (Ac-LKKTETQ).

Browse Regenerative & Cytoprotective researchHow to read a COA
áFor Research Use Only · Not for human or veterinary use · Not for diagnostic or therapeutic use

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